Wroclaw University of Science and Technology carries out a project titled “University of New Opportunities”. Within the frames of this project a Digital Accessibility Guide (DAG) is developed with the aim to provide comprehensive information on the university’s facilities with special emphasis on people with disabilities. The Analytical Hierarchy Process (AHP) methodology was applied to select the 25 facilities to be included in the DAG. The proposed methodology included development of a hierarchical structure of the model, the determination of seven evaluation criteria, adoption of a scoring scale (1–5) of subcriteria for each criterion, and their pairwise comparison by an interdisciplinary group of experts. The selected criteria comprised of the functions and services of buildings, the number of users, communication and architectural accessibility, the number of indications in the accessibility survey and the number of classrooms. The final ranking of facilities was created based on the evaluated characteristics of nearly fifty buildings and the results of the AHP evaluation of the selection criteria and their weights. The consensus of the expert group involved in the pairwise comparison was 2.8% and the weighted score of the facilities ranged from 4.68 to 1.29 with a median of 2.16. The applied approach structured the decision problem in accordance with the multicriterial decision analysis approach. The proposed methodology for selecting the University's strategic facilities is universal and may be used in other universities.