Russia’s military aggression against Ukraine has become a serious challenge for the Ukrainian labor market, leading to significant disproportions, which are reflected in the imbalance of supply and demand for labor, large-scale loss of jobs, the fall in real wages and incomes, as well as significant structural and regional imbalances in the functioning of the labor market, which deepens the uneven development of the Ukrainian economy and poses a threat to the economic security of Ukraine. These processes, taking into account a number of problems in the socio-economic development of Ukraine in the pre-war period, threaten the economic and social security of Ukraine in the short and long term, causing significant economic losses and degradation of human capital. The prospects of the post-war development of the Ukrainian labor market should primarily be considered in the context of the formation of a safe economic and social environment at the state level, the imperative of which should be the preservation of human capital in Ukraine. For this purpose, a state strategy for the post-war recovery of the national economy with a clearly expressed socio-humanitarian orientation should be developed, which will provide for the observance of social guarantees at the level of leading international standards. At the same time, it is equally important to stimulate economic growth in Ukraine on the basis of intellectualization, digitalization, and environmentalization of the Ukrainian economy.