Polish road transport is number one in Europe, accounting for over 20% of freight transport on the old continent. It is also directly responsible for 6% of Poland’s GDP. However, since the outbreak of the Covid-19 pandemic, a huge crisis has been noticeable, which, combined with many smaller ones, has escalated to the most serious in over 20 years. The aim of this paper is to discuss the key reasons for the crisis in the Polish road transport industry and to show the actual consequences of these problems. The study was conducted in a descriptive form using data analysis from reports by major road transport organizations, a review of scientific literature, observation and analysis of real cases. It was found that the impact on this industry in a single period of challenges related to the pandemic, economic, war in Ukraine, shortage of drivers, and EU policy. The emergence of so many sudden changes and unusual situations forced many companies to reduce their fleets and, in the worst cases, led to restructuring or bankruptcy. As a result, the study showed that these situations were significantly reflected in the crisis that affected the Polish road transport industry. The conclusion was that carriers were forced to adapt to the current situation, which was referred to as their new reality. It was also established that a responsible approach is key in this situation, which must be focused on flexible action and adaptation to the current conditions imposed by global and local crises.