Contemporary distribution centers face the challenge of evolving toward operational models aligned with Industry 5.0 principles. To analyze LPP’s transformation potential, this study uses SWOT + MAM methodology, which sequentially employs SWOT analysis, Mind Mapping, and Morphological analysis to assess organizational readiness and generate strategic solutions. This article also describes a new, previously almost entirely overlooked proposal to combine the SWOT and MAM methodologies in a single work. The analysis of LPP’s current infrastructure reveals significant automation capabilities through cross-belt sorters processing 5,000 packages per hour and the proprietary Control Tower platform enabling real-time supply chain transparency. The company possesses strong foundations in sustainable development, as evidenced by BREEAM Excellent certifications, and experience in green initiatives. Morphological analysis identifies two equivalent transformation pathways: a high-autonomy warehouse system integrating AutoStore technology with renewable energy sources and dedicated cybersecurity infrastructure, and a partially autonomous model featuring AI-enhanced security combined with drone-based logistics and RFID identification systems. Both solutions received identical 22-point evaluations across criteria including novelty, feasibility, rationality, originality, usefulness. These results indicate that the Industry 5.0 transition at LPP focuses primarily on sustainability as its main transformation driver, with organizational resilience in second place, while human-centricity aspects require further development. The SWOT + MAM methodology proves effective in the comprehensive strategic assessment of transition towards Industry 5.0 and in establishing practical frameworks for this process.