The work presents the concept of applying a simulated annealing algorithm to humancomputer interface optimization. The essence of this proposal lies in taking into account criteria deciding about the ergonomic quality of the signaling and control panel within the simulated annealing perspective. Moreover, a simple concept of mapping objects’ sizes to the modular grid by means of artificial elements connected with each other in a specific way has been proposed. The effectiveness of this approach has been shown in simulation experiments involving interfaces that included components of various geometrical dimensions. The examination included also CRAFT methodology. The comparison of our version of the algorithm with the classical CRAFT methodology is promising and inclines for further developing this approach and investigating its properties.